News from NYU Langone Health
Parents Annoyed With “Roommates From Hell” College Kids Coming Home For The Summer — But They’re Taking Action. (New York Post)
(6/12) Yamalis Diaz, PhD, clinical associate professor, Department of Child and Adolescent Psychiatry, explains the “tug-of-war” between parents and their college-attending children returning home for the summer, as young adults explore self-identity and independence, often leading to conflicts over household rules, noting, “During this developmental stage, kids are transitioning out of adolescence and into adulthood.”
Dr Huang On The FDA Approval Of Mitomycin Intravesical Solution For Recurrent, Low-Grade, Intermediate-Risk NMIBC. (OncLive)
(6/12) William C. Huang, MD, vice chair for clinical affairs, professor, Department of Urology, and professor, Department of Radiology, chief, urology service, Tisch Hospital, Perlmutter 鶹Ƶapp Center, discussed the FDA’s approval of the mitomycin intravesical solution (Zusduri; UGN-102) for treating recurrent, low-grade, intermediate-risk non–muscle-invasive bladder cancer (NMIBC), highlighting its potential to shift treatment from surgical to nonsurgical and chemoablative methods, with the approval based on the phase 3 ENVISION trial’s findings, showing a 3-month complete response rate of 78% and a 12-month duration of response rate of 79%, supported by data from earlier trials like OPTIMA II and ATLAS.
Blood-Based Screening Has Acceptable Accuracy For Colorectal 鶹Ƶapp Detection. (HealthDay)
(6/12) A study published in the Journal of the American Medical Association, led by Aasma Shaukat, MD, MPH, the Robert M. and Mary H. Glickman Professor of Medicine, Department of Medicine, Division of Gastroenterology and Hepatology, professor, Department of Population Health, examined the clinical performance of a blood-based circulating tumor DNA test for colorectal cancer detection in a cohort of 27,010 asymptomatic adults aged 45 to 85; the test showed a sensitivity of 79.2% for colorectal cancer and specificity of 91.5% for advanced colorectal neoplasia, but only a 12.5% sensitivity for advanced precancerous lesions, indicating a need for improved test sensitivity, with funding disclosed from biopharmaceutical companies including Freenome Holdings Inc.
AI-Based Tool Aims To Optimize MRI Use In Prostate 鶹Ƶapp Diagnosis. (Urology Times)
(6/12) A machine learning tool called ProMT-ML has been developed to optimize MRI use in prostate cancer diagnosis, particularly addressing prolonged wait times and diagnostic delays, especially in under-resourced or rural settings, by predicting which patients should receive timely MRI scans based on data such as PSA levels, prostate volume, and body mass index; Madhur Nayan, MD, PhD, assistant professor, Departments of Urology, and Population Health, said, “I’m excited to see how these models are going to continue to be developed and applied in clinical practice, because precision medicine is here, and I’m looking forward to it.”
Mitochondrial Genetics Key To Metastatic Melanoma Immunotherapy Resistance. (HealthDay)
(6/12) Kelsey R. Monson, PhD, postdoctoral research fellow, Department of Population Health, Division of Epidemiology, Perlmutter 鶹Ƶapp Center Center, and colleagues found that patients with metastatic melanoma belonging to mitochondrial haplogroup T (HG-T) show resistance to anti-programmed cell death protein-1-based immune checkpoint inhibitors, both as a single agent and in combination, as reported in a study published in Nature Medicine; Monson said, “Checkpoint immunotherapy has become the mainstay in cancer care in the past decade, especially for those with metastatic melanoma, but until now, it has never been clearly explained why nearly half will not respond to treatment.”
HS Genetics Point Toward The Hair Growth Cycle. (Medscape)
(6/13) A genome-wide association study (GWAS) has uncovered a missense variant, rs121908120-A, in the WNT10A pathway, which may be protective against hidradenitis suppurativa (HS), suggesting that targeting hair follicle biology could be a promising direction for drug development, according to a letter led by Olivia D. Perez, MD, postdoctoral fellow, The Ronald O. Perelman Department of Dermatology; the letter, published in the Journal of the American Academy of Dermatology, also explores the genetic underpinnings of HS and its implications for reducing stigma and improving treatment strategies.
How One State Reduced Its Overdose Death Rate By 32% In A Year. (WJAX-TV Jacksonville (FL))
Jacksonville, FL (6/12) Overdose deaths in New York state decreased by 32% from 2023 to 2024, attributed to expanded harm reduction and addiction treatment services, including the distribution of naloxone, fentanyl, and xylazine test strips, and opioid settlement funds, according to provisional CDC data and Gov. Kathy Hochul’s administration; Dr. Magdalena Cerdá, DrPH, professor, Department of Population Health, said the decline mirrors a national trend, though racial disparities persist, with overdose deaths unchanged among Black New Yorkers and increased among Latino New Yorkers, highlighting the need for equitable distribution of resources, as emphasized by the Opioid Settlement Fund Advisory Board, amidst concerns of federal funding cuts to addiction services.
Staying ‘As Mobile As Possible’ Critical To Curbing Osteoporosis In Rheumatoid Arthritis. (Healio)
(6/12) Managing osteoporosis in rheumatoid arthritis (RA) requires a comprehensive, multidisciplinary approach to prevent bone loss, fractures, and falls, with Rachel Pessah-Pollack, MD, clinical professor, Department of Medicine, the Holman Division of Endocrinology, Diabetes & Metabolism, saying, “Unfortunately, by the time I see these patients, they are to the point of having already low bone mass,” highlighting the need for early intervention.
Worried About Your Vision On Ozempic Or Wegovy? Read This First. (Women's World Magazine)
(6/12) Semaglutide medications, including Ozempic and Wegovy, have been linked to an increased risk of developing nonarteritic anterior ischemic optic neuropathy (NAION), a rare eye condition that can lead to blindness, prompting the European Medicines Agency to recommend Novo Nordisk update its product information to include this as a very rare side effect, with Rachel Pessah-Pollack, MD, clinical professor, Department of Medicine, the Holman Division of Endocrinology, Diabetes & Metabolism, explaining, “NAION happens when blood flow to the optic nerve is blocked. It can cause the sudden, painless loss of vision in one eye,” and emphasizing the need for further research to determine the cause of the increased risk.
13 Expert-Backed Foods That Fuel Muscle Growth And Recovery. (Vogue (IND))
(6/13)Among 13 expert-recommended foods that support muscle growth and recovery, Greek yoghurt is praised by Heather A. Hodson, RDN, CDN, CDCES, dietitian nutritionist, Center for the Prevention of Cardiovascular Disease, for having nearly twice the protein of regular yoghurt while being low in carbohydrates, making it an effective post-workout option that tastes like dessert.
4 Grocery Store Items Colon 鶹Ƶapp Doctors Avoid – And 3 They Love. (Insider)
(6/12) Paul E. Oberstein, MD, associate professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter 鶹Ƶapp Center, specializing in gastrointestinal cancers, discussed dietary considerations for colon cancer patients, expressing skepticism about the impact of individual foods like avocados or pine nuts on cancer recurrence while emphasizing broader dietary patterns.
The Painful Truth About What Really Happens To Ballet Dancers’ Feet. (Women's Health)
(6/12) Recent portrayals of ballerinas in media emphasize the physical challenges of ballet, prompting experts to highlight the importance of proper pointe shoe fitting to prevent injuries, with Lauren E. Borowski, MD, assistant professor, Department of Orthopedic Surgery, Sports Medicine Center, saying, “It’s not one size fits all,” and recommending “working with a good fitter, not just buying something off the internet for the first time.”
Can Ozempic Make Your Penis Look Bigger? (Verywell Health)
(6/12) Some men on social media have reported an increase in perceived penis size after taking Ozempic (semaglutide), though this is likely due to weight loss revealing more of the external penile length rather than a direct effect of the medication, according to physicians including Hossein Sadeghi-Nejad, MD, professor, Departments of Urology, and Obstetrics and Gynecology, who said, “Weight loss will often result in improved cardiometabolic health and resultant improved erections due to better blood flow,” while also noting that Ozempic is unlikely to directly affect penile length or girth
News from NYU Langone Hospital—Long Island
NYU Langone Hospital – Long Island Cuts Stroke Intervention Time By 35%. (Becker's Hospital Review)
(6/12) NYU Langone Hospital—Long Island decreased the time from door-to-activation of the neurointerventional radiology team by 12.5 minutes, or 35.2%, for stroke patients through simulation training involving medical residents, physician assistants, and stroke team members.