NYU Langone Health experts break down the science of longevity—sharing practical, evidence-based ways to extend your vitality.
Credit: NYU Langone
Longevity was once defined as simply living longer. Today it’s about living better for longer—adding more healthy, active years to life.
As conversations around health span and longevity surge across social media and the news, so does misinformation. Between supplements, hormone therapies, and viral wellness trends, it can be difficult to separate what’s helpful from what’s hype.
To bring clarity, physicians across NYU Langone Health—including experts in sports medicine, orthopedics, endocrinology, internal medicine, men’s and women’s health, and mental health—came together to break down what actually supports long-term health and what may not.
Their biggest piece of advice: Start small. A few manageable changes to your daily routine can lead to lasting benefits.
Longevity Is About More Than Lifespan
For many people, longevity is still tied to a number. But experts agree that that definition is outdated.
“It’s one thing to want to live to 90,” said Steven Lamm, MD, an internal medicine specialist and the medical director of NYU Langone’s Preston Robert Tisch Center for Men’s Health. “It’s another to be vibrant and able to enjoy those years.”
Instead, physicians emphasize health span—the number of years a person remains healthy, independent, and fully engaged in life.
“It’s not just about living longer,” said Dr. Lamm. “It’s about maintaining a strong physical, social, and psychological state as you age.”
Why “Quick Fix” Trends Miss the Mark
Many patients are drawn to quick solutions—whether it’s supplements, hormone therapies, or trending treatments online. But those approaches may oversimplify complex systems.
“People are looking for a quick fix, but longevity isn’t about one thing—it’s about small steps that make a difference,” said Thea Gallagher, PsyD, a clinical psychologist and the director of Wellness Programs in the at NYU Langone.
Physicians say the rise of wellness trends—from peptide injections to hormone optimization—has made it harder for patients to distinguish evidence-based care from unproven approaches.
“We’re seeing how mainstream some of these treatments have become,” said Elizabeth Comen, MD, a breast oncologist and co-director of the Mignone Women’s Health Collaborative at NYU Langone. “But it’s our responsibility to meet patients where they are and help them understand what’s grounded in science and what isn’t.”
That mindset often extends to supplements and nutrition trends.
“Despite how popular supplements have become, most people don’t need them unless they have a true deficiency,” said Rachel Pessah-Pollack, MD, an endocrinologist in the Department of Medicine’s at NYU Langone. “When you take them without a clear need, you’re often not getting added benefit.”
Dr. Pessah-Pollack noted that, when appropriate, supplements should be tailored to the individual—whether that’s calcium for bone health or B12 and iron for deficiencies—but they’re not a substitute for a healthy diet or a shortcut to better health.
She encourages making dietary changes whenever possible before relying on a supplement. For calcium-deficient patients, she will first recommend drinking an extra glass of almond milk every day. If that isn’t accessible for her patients, then she will prescribe a supplement.
Hormone therapies are another area where misinformation is common. Similar to supplements, testosterone or estrogen therapy should only be considered when clinically appropriate.
“Depending on the patient’s age, lifestyle, and symptoms, I may prescribe testosterone therapy,” said Dr. Lamm. “There are side effects patients need to be aware of, including impacts on fertility.”
Dr. Pessah-Pollack added that hormone replacement therapy, particularly during menopause, can be beneficial for some patients—but it’s not a one-size-fits-all solution.
The Foundation: Sleep, Movement, Nutrition, and Connection
While trends come and go, the fundamentals of long-term health remain consistent. Experts point to four core pillars that support longevity: sleep, movement, nutrition, and social connection.
“We often focus on the extras, but it’s really the basics that make the biggest difference,” said Guillem Gonzalez-Lomas, MD, an orthopedic sports medicine surgeon at NYU Langone.
Regular movement—whether structured exercise or daily activity—is key.
“Doing something every day matters,” he said. “It can be as simple as taking the stairs, going for a walk, or dancing at home.”
He emphasized that exercise doesn’t need to be rigid or expensive to be effective, and that activities done with others can offer both physical and social benefits.
Nutrition also plays a central role, though experts caution against overcomplicating it.
“Protein is important, especially as we age, but more isn’t always better,” said Dr. Gonzalez-Lomas. “There’s a point where excess intake isn’t beneficial and may even strain the body.”
Instead, he recommends focusing on a balanced diet that includes a variety of whole foods.
Mental and social health are equally critical—but often overlooked.
“Social connection sounds simple, but it can be difficult to implement,” said Dr. Gallagher. “There are real barriers—time, stress, even embarrassment—but small steps can make a big difference.”
Practices like mindfulness, setting boundaries, and maintaining relationships can have meaningful impacts on both mental and physical health over time.
Prevention Is a Lifelong Strategy
Prevention also plays a critical role in extending health span.
“Longevity isn’t just about adding years—it's about reducing your risk of disease across your lifetime,” said Dr. Comen. “That means understanding your personal risk factors and staying up to date with screenings.”
Many chronic illnesses, including heart disease, cancer, and metabolic disorders, can be better managed—or even avoided—with earlier detection and lifestyle changes.
“We have the tools to monitor things like cholesterol, blood sugar, and bone health,” said Dr. Pessah-Pollack. “The key is using them proactively and in an evidence-based way.”
Start Early—but It’s Never Too Late
While healthy habits in your 20s and 30s can set the foundation for long-term health, experts stress that it’s never too late to make changes.
“You can reduce illness significantly by focusing on healthy behaviors,” said Dr. Lamm. “Even later in life, small changes can have a meaningful impact.”
Maintaining muscle mass, supporting bone health, and staying physically active become especially important with age.
“Your muscle mass is what helps keep you functional and independent,” said Dr. Pessah-Pollack. “That’s a key part of staying vital as you get older.”
Small Changes Add Up Over Time
Ultimately, longevity isn’t about perfection; it’s about consistency.
“Start with something very small,” said Dr. Gallagher. “Whether it’s a 10-minute walk, reading for a few minutes, or setting a regular sleep schedule, those habits build over time.” Experts say the goal isn’t to overhaul your life overnight but to make sustainable changes that become part of your routine.
“The basics may not be flashy,” said Dr. Gonzalez-Lomas, “but they’re what actually work.”
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